β-barrel mobility underlies closure of the voltage-dependent anion channel

The voltage-dependent anion channel (VDAC) is the major protein in the outer membrane of mitochondria, where it mediates efficient transport of ATP and ADP. Changes in its conformation and permeability, induced by voltage or apoptosis-related proteins, have been implicated in apoptotic pathways. The...

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Dettagli Bibliografici
Pubblicato in:Structure
Autori principali: Zachariae, Ulrich, Schneider, Robert, Briones, Rodolfo, Gattin, Zrinka, Demers, Jean-Philippe, Giller, Karin, Maier, Elke, Zweckstetter, Markus, Griesinger, Christian, Becker, Stefan, Benz, Roland, de Groot, Bert L., Lange, Adam
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650048/
https://ncbi.nlm.nih.gov/pubmed/22841291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.06.015
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