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Medium-throughput screen of microbially produced serotonin via a GPCR-based sensor

Chemical biosensors, where chemical detection triggers a fluorescent signal, have the potential to accelerate the screening of non-colorimetric chemicals produced by microbes, enabling the high-throughput engineering of enzymes and metabolic pathways. Here, we engineer a GPCR-based sensor to detect...

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Vydáno v:Biochemistry
Hlavní autoři: Ehrenworth, Amy M., Claiborne, Tauris, Peralta-Yahya, Pamela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654487/
https://ncbi.nlm.nih.gov/pubmed/28845660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00605
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