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Transcriptional Coupling of Neighboring Genes and Gene Expression Noise: Evidence that Gene Orientation and Noncoding Transcripts Are Modulators of Noise

How is noise in gene expression modulated? Do mechanisms of noise control impact genome organization? In yeast, the expression of one gene can affect that of a very close neighbor. As the effect is highly regionalized, we hypothesize that genes in different orientations will have differing degrees o...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Wang, Guang-Zhong, Lercher, Martin J., Hurst, Laurence D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654408/
https://ncbi.nlm.nih.gov/pubmed/21402863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr025
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