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Transcriptional Coupling of Neighboring Genes and Gene Expression Noise: Evidence that Gene Orientation and Noncoding Transcripts Are Modulators of Noise

How is noise in gene expression modulated? Do mechanisms of noise control impact genome organization? In yeast, the expression of one gene can affect that of a very close neighbor. As the effect is highly regionalized, we hypothesize that genes in different orientations will have differing degrees o...

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Détails bibliographiques
Publié dans:Genome Biol Evol
Auteurs principaux: Wang, Guang-Zhong, Lercher, Martin J., Hurst, Laurence D.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654408/
https://ncbi.nlm.nih.gov/pubmed/21402863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr025
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