Systemic Administration of an Alpha-7 Nicotinic Acetylcholine Agonist Reverses Neuropathic Pain in Male Sprague Dawley Rats

Alpha-7 nicotinic acetylcholine receptor (α7 nAChR) agonists attenuate pain and inflammation in preclinical models. This study tested whether systemic delivery of an α7 nAChR agonist attenuates neuropathic pain and associated immune-mediated pro-inflammation. Hind paw response thresholds to mechanic...

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Detaylı Bibliyografya
Yayımlandı:J Pain
Asıl Yazarlar: Loram, Lisa C., Taylor, Frederick R., Strand, Keith A., Maier, Steven F., Speake, Jason D., Jordan, Kristen G., James, John W., Wene, Steven P., Pritchard, Robert C., Green, Heather, Van Dyke, Katherine, Mazarov, Anatoly, Letchworth, Sharon R., Watkins, Linda R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654381/
https://ncbi.nlm.nih.gov/pubmed/23182225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2012.08.009
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