The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo

OBJECTIVE: The aim of this work was to compare the early gene expression profiles in the skin of HPV16-E6 transgenic mice regulated by the E6 PDZ-binding motif. MATERIALS AND METHODS: The global transcriptional profiles in dorsal skin biopsies from K14E6 and K14E6Δ146-151 transgenic mice were compar...

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Udgivet i:Biomed Res Int
Main Authors: Cortés-Malagón, Enoc Mariano, Palacios-Reyes, Carmen, Romero-Cordoba, Sandra, Mendoza-Villanueva, Daniel, Escobar-Herrera, Jaime, Verdejo-Torres, Odette, Contreras, Rubén Gerardo, Fernádez-Tilapa, Gloria, Moreno-Eutimio, Mario Adan, Moreno, José, Hidalgo-Miranda, Alfredo, Gariglio, Patricio, Bonilla-Delgado, José
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654334/
https://ncbi.nlm.nih.gov/pubmed/29130045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7868645
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