HPV16-E6 Oncoprotein Activates TGF-β and Wnt/β-Catenin Pathways in the Epithelium-Mesenchymal Transition of Cataracts in a Transgenic Mouse Model

OBJECTIVE: This work aimed to determine if cataractous changes associated with EMT occurring in the K14E6 mice lenses are associated with TGF-β and Wnt/β-catenin signaling activation. MATERIALS AND METHODS: Cataracts of K14E6 mice were analysed histologically; and components of TGF-β and Wnt/β-caten...

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Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Rodríguez-Uribe, Genaro, Serafín-Higuera, Nicolas, Damian-Morales, Gabriela, Cortés-Malagón, Enoc Mariano, García-Hernández, Vicky, Verdejo-Torres, Odette, Campos-Blázquez, Jessica Paulina, Trejo-Muñoz, Cynthia R., Contreras, Rubén Gerardo, Ocadiz-Delgado, Rodolfo, Palacios-Reyes, Carmen, Lambert, Paul F., Griep, Anne E., Mancilla-Percino, Teresa, Escobar-Herrera, Jaime, Álvarez-Ríos, Elizabeth, Ugarte-Briones, Carlos, Moreno, José, Gariglio, Patricio, Bonilla-Delgado, José
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977056/
https://ncbi.nlm.nih.gov/pubmed/29888254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2847873
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