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Clonal dominance and transplantation dynamics in hematopoietic stem cell compartments

Hematopoietic stem cells in mammals are known to reside mostly in the bone marrow, but also transitively passage in small numbers in the blood. Experimental findings have suggested that they exist in a dynamic equilibrium, continuously migrating between these two compartments. Here we construct an i...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ashcroft, Peter, Manz, Markus G., Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654265/
https://ncbi.nlm.nih.gov/pubmed/28991922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005803
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