Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway

Amphotericin B (AmB) induces oxidative and nitrosative stresses, characterized by production of reactive oxygen and nitrogen species, in fungi. Yet, how these toxic species contribute to AmB-induced fungal cell death is unclear. We investigated the role of superoxide and nitric oxide radicals in AmB...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Vriens, Kim, Kumar, Phalguni Tewari, Struyfs, Caroline, Cools, Tanne L., Spincemaille, Pieter, Kokalj, Tadej, Sampaio-Marques, Belém, Ludovico, Paula, Lammertyn, Jeroen, Cammue, Bruno P. A., Thevissen, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654257/
https://ncbi.nlm.nih.gov/pubmed/29129987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4064628
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