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Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases

The homeostasis of iron is vital to human health, and iron dyshomeostasis can lead to various disorders. Iron homeostasis is maintained by iron regulatory proteins (IRP1 and IRP2) and the iron-responsive element (IRE) signaling pathway. IRPs can bind to RNA stem-loops containing an IRE in the untran...

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Pubblicato in:Mol Neurodegener
Autori principali: Zhou, Zhi Dong, Tan, Eng-King
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654065/
https://ncbi.nlm.nih.gov/pubmed/29061112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0218-4
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