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Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases

The homeostasis of iron is vital to human health, and iron dyshomeostasis can lead to various disorders. Iron homeostasis is maintained by iron regulatory proteins (IRP1 and IRP2) and the iron-responsive element (IRE) signaling pathway. IRPs can bind to RNA stem-loops containing an IRE in the untran...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Zhou, Zhi Dong, Tan, Eng-King
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654065/
https://ncbi.nlm.nih.gov/pubmed/29061112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0218-4
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