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IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis

Chronic inflammation is a critical component of atherogenesis, however, reliable human translational models aimed at characterizing these mechanisms are lacking. Psoriasis, a chronic inflammatory skin disease associated with increased susceptibility to atherosclerosis, provides a clinical human mode...

Ausführliche Beschreibung

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Veröffentlicht in:Sci Rep
Hauptverfasser: Mehta, Nehal N., Teague, Heather L., Swindell, William R., Baumer, Yvonne, Ward, Nicole L., Xing, Xianying, Baugous, Brooke, Johnston, Andrew, Joshi, Aditya A., Silverman, Joanna, Barnes, Drew H., Wolterink, Liza, Nair, Rajan P., Stuart, Philip E., Playford, Martin, Voorhees, John J., Sarkar, Mrinal K., Elder, James T., Gallagher, Katherine, Ganesh, Santhi K., Gudjonsson, Johann E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653789/
https://ncbi.nlm.nih.gov/pubmed/29062018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14365-1
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