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Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy

Exercise induces expression of the myokine irisin, which is known to promote browning of white adipose tissue and has been shown to mediate beneficial effects following exercise. Here we show that irisin induces expression of a number of pro-myogenic and exercise response genes in myotubes. Irisin i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Reza, Musarrat Maisha, Subramaniyam, Nathiya, Sim, Chu Ming, Ge, Xiaojia, Sathiakumar, Durgalakshmi, McFarlane, Craig, Sharma, Mridula, Kambadur, Ravi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653663/
https://ncbi.nlm.nih.gov/pubmed/29062100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01131-0
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