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Drug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics

BACKGROUND: Our previous study suggested NR4A2, a subfamily member of orphan nuclear receptors, is essential for survival of human cancer cells such as mucoepidermoid carcinoma (MEC). METHODS: We conducted high throughput drug screening for NR4A2 inhibitors as a novel therapeutic modality. Positive...

詳細記述

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書誌詳細
出版年:Transl Lung Cancer Res
主要な著者: Komiya, Takefumi, Yamamoto, Satomi, Roy, Anuradha, McDonald, Peter, Perez, Raymond P.
フォーマット: Artigo
言語:Inglês
出版事項: AME Publishing Company 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653521/
https://ncbi.nlm.nih.gov/pubmed/29114475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2017.07.02
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