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Drug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics

BACKGROUND: Our previous study suggested NR4A2, a subfamily member of orphan nuclear receptors, is essential for survival of human cancer cells such as mucoepidermoid carcinoma (MEC). METHODS: We conducted high throughput drug screening for NR4A2 inhibitors as a novel therapeutic modality. Positive...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Komiya, Takefumi, Yamamoto, Satomi, Roy, Anuradha, McDonald, Peter, Perez, Raymond P.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653521/
https://ncbi.nlm.nih.gov/pubmed/29114475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2017.07.02
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