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Direct Screening of Enzyme Activity using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI)
RATIONALE: High-throughput screening (HTS) is a critical step in the drug discovery process. However, most mass spectrometry-based HTS methods require sample cleanup steps prior to analysis. In this work we present the utility of infrared matrix-assisted laser desorption electrospray ionization (IR-...
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| Опубликовано в: : | Rapid Commun Mass Spectrom |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653407/ https://ncbi.nlm.nih.gov/pubmed/28841760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.7971 |
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