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Characterization of Intramolecular Interactions of Cytochrome c Using Hydrogen Deuterium Exchange - Trapped Ion Mobility Spectrometry– Mass Spectrometry and Molecular Dynamics

Globular proteins, such as cytochrome c (cyt c), display an organized native conformation, maintained by a hydrogen bond interaction network. In the present work, the structural interrogation of kinetically trapped intermediates of cyt c was performed by correlating the ion-neutral collision cross s...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Molano-Arevalo, Juan Camilo, Dit Fouque, Kevin Jeanne, Pham, Khoa, Miksovska, Jaroslava, Ridgeway, Mark E., Park, Melvin A., Fernandez-Lima, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653375/
https://ncbi.nlm.nih.gov/pubmed/28742962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b00844
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