Silencing Aurora A leads to re-sensitization of breast cancer cells to Taxol through downregulation of SRC-mediated ERK and mTOR pathways

While Taxol has been reported to improve the clinical survival of breast cancer patients, subsequently developed drug-resistance of the cancer cells limits its final efficacy and applications. Previous studies suggested that Aurora A is involved in the development of the Taxol-resistance of breast c...

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Bibliographic Details
Published in:Oncol Rep
Main Authors: Li, Yan, Zhou, Wanqi, Tang, Ke, Chen, Xiaoguang, Feng, Zhiqiang, Chen, Jindong
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652950/
https://ncbi.nlm.nih.gov/pubmed/28849180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5908
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