Possible involvement of ROS generation in vorinostat pretreatment induced enhancement of the antibacterial activity of ciprofloxacin

The mechanism underlying ciprofloxacin action involves interference with transcription and replication of bacterial DNA and, thus, the induction of double-strand breaks in DNA. It also involves elevated oxidative stress, which might contribute to bacterial cell death. Vorinostat was shown to induce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Pharmacol
Egile Nagusiak: Masadeh, Majed M, Alzoubi, Karem H, Al-azzam, Sayer I, Al-buhairan, Ahlam M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2017
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652917/
https://ncbi.nlm.nih.gov/pubmed/29081676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S148448
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