Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients

As predictive markers for anti-EGFR therapy, KRAS and BRAF mutations are routinely detected in primary and metastatic colorectal cancer (CRC) cells, but seldom in circulating tumor cells (CTCs). Detecting mutations in CTCs could help explain mutational differences between tumor cells at local sites...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Liu, Yong, Meucci, Stefano, Sheng, Liming, Keilholz, Ulrich
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Meta-Analysis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652825/
https://ncbi.nlm.nih.gov/pubmed/29100436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18272
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