Meta-analysis of the mutational status of circulation tumor cells and paired primary tumor tissues from colorectal cancer patients

As predictive markers for anti-EGFR therapy, KRAS and BRAF mutations are routinely detected in primary and metastatic colorectal cancer (CRC) cells, but seldom in circulating tumor cells (CTCs). Detecting mutations in CTCs could help explain mutational differences between tumor cells at local sites...

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Publicado en:Oncotarget
Main Authors: Liu, Yong, Meucci, Stefano, Sheng, Liming, Keilholz, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Meta-Analysis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652825/
https://ncbi.nlm.nih.gov/pubmed/29100436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18272
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