Ascites-derived IL-6 and IL-10 synergistically expand CD14(+)HLA-DR(-/low) myeloid-derived suppressor cells in ovarian cancer patients

Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various types of cancer, including ovarian cancer (OC). In this study, we characterized CD14(+)HLA-DR(–/lo) MDSC with a typical monocytic phenotype (M-MDSC) in the peripheral blood (PB) and ascites from OC patients. Compare...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Liangliang, Deng, Zhaoyang, Peng, Yaojun, Han, Lu, Liu, Jing, Wang, Linxiong, Li, Bohua, Zhao, Jian, Jiao, Shunchang, Wei, Huafeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652747/
https://ncbi.nlm.nih.gov/pubmed/29100353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20164
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