Combination immunohistochemistry for SMAD4 and Runt-related transcription factor 3 may identify a favorable prognostic subgroup of pancreatic ductal adenocarcinomas

PURPOSES: SMAD4/DPC4 mutations have been associated with aggressive behavior in pancreatic ductal adenocarcinomas (PDAC), and it has recently been suggested that RUNX3 expression combined with SMAD4 status may predict the metastatic potential of PDACs. We evaluated the prognostic utility of SMAD4/RU...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lee, Yangkyu, Lee, Hyejung, Park, Hyunjin, Kim, Jin-Won, Hwang, Jin-Hyeok, Kim, Jaihwan, Yoon, Yoo-Seok, Han, Ho-Seong, Kim, Haeryoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652736/
https://ncbi.nlm.nih.gov/pubmed/29100342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20815
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