Combination immunohistochemistry for SMAD4 and Runt-related transcription factor 3 may identify a favorable prognostic subgroup of pancreatic ductal adenocarcinomas

PURPOSES: SMAD4/DPC4 mutations have been associated with aggressive behavior in pancreatic ductal adenocarcinomas (PDAC), and it has recently been suggested that RUNX3 expression combined with SMAD4 status may predict the metastatic potential of PDACs. We evaluated the prognostic utility of SMAD4/RU...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Lee, Yangkyu, Lee, Hyejung, Park, Hyunjin, Kim, Jin-Won, Hwang, Jin-Hyeok, Kim, Jaihwan, Yoon, Yoo-Seok, Han, Ho-Seong, Kim, Haeryoung
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652736/
https://ncbi.nlm.nih.gov/pubmed/29100342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20815
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