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Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells

Microtentacles are mostly microtubule-based cell protrusions that are formed by detached tumor cells. Here, we report that the formation of tumor cell microtentacles depends on the presence and dynamics of guanine nucleotide-binding proteins of the septin family, which are part of the cytoskeleton....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Østevold, Kristine, Meléndez, Ana V., Lehmann, Friederike, Schmidt, Gudula, Aktories, Klaus, Schwan, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652735/
https://ncbi.nlm.nih.gov/pubmed/29100341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20805
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