Functional consequence of the p53 codon 72 polymorphism in colorectal cancer

BACKGROUND: The codon 72 polymorphism in p53 has been implicated in colorectal cancer (CRC) risk, prognosis and CRC health disparities. We examined the functional consequence of this polymorphism in CRC. EXPERIMENTAL DESIGN: Plasmids (pCMV6) that express different phenotypes of p53 [p53 wild type (w...

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Publicado en:Oncotarget
Autores principales: Katkoori, Venkat R., Manne, Upender, Chaturvedi, Lakshmi S., Basson, Marc D., Haan, Pam, Coffey, Daniel, Bumpers, Harvey L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652727/
https://ncbi.nlm.nih.gov/pubmed/29100333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20580
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