Functional consequence of the p53 codon 72 polymorphism in colorectal cancer

BACKGROUND: The codon 72 polymorphism in p53 has been implicated in colorectal cancer (CRC) risk, prognosis and CRC health disparities. We examined the functional consequence of this polymorphism in CRC. EXPERIMENTAL DESIGN: Plasmids (pCMV6) that express different phenotypes of p53 [p53 wild type (w...

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發表在:Oncotarget
Main Authors: Katkoori, Venkat R., Manne, Upender, Chaturvedi, Lakshmi S., Basson, Marc D., Haan, Pam, Coffey, Daniel, Bumpers, Harvey L.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652727/
https://ncbi.nlm.nih.gov/pubmed/29100333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20580
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