The farnesoid X receptor negatively regulates osteoclastogenesis in bone remodeling and pathological bone loss

Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Since the role of FXR in osteoclast differentiation remains ill-defined, we investigated the biological function of FXR on osteoclastogenesis, using FXR-deficient mice. We dem...

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Vydáno v:Oncotarget
Hlavní autoři: Zheng, Ting, Kang, Ju-Hee, Sim, Jung-Sun, Kim, Jung-Woo, Koh, Jeong-Tae, Shin, Chan Soo, Lim, Hyungsik, Yim, Mijung
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652726/
https://ncbi.nlm.nih.gov/pubmed/29100332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20576
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