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The farnesoid X receptor negatively regulates osteoclastogenesis in bone remodeling and pathological bone loss
Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Since the role of FXR in osteoclast differentiation remains ill-defined, we investigated the biological function of FXR on osteoclastogenesis, using FXR-deficient mice. We dem...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652726/ https://ncbi.nlm.nih.gov/pubmed/29100332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20576 |
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