High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor antagonism

High-fat diet (HFD)-induced obesity is reaching worldwide proportions. In addition to causing obesity, HFDs also induce a variety of health disorders, which includes cognitive decline. Hippocampal function may be particularly vulnerable to the negative consequences of HFD, and it is suspected that ‘...

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Publicado en:Brain Behav Immun
Autores principales: Sobesky, Julia L., Barrientos, Ruth M., De May, Henning S., Thompson, Brittany M., Weber, Michael D., Watkins, Linda R., Maier, Steven F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652296/
https://ncbi.nlm.nih.gov/pubmed/24998196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.06.017
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