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Peripheral Neuropathy and Hindlimb Paralysis in a Mouse Model of Adipocyte-Specific Knockout of Lkb1

Brown adipose tissues (BAT) burn lipids to generate heat through uncoupled respiration, thus representing a powerful target to counteract lipid accumulation and obesity. The tumor suppressor liver kinase b1 (Lkb1) is a key regulator of cellular energy metabolism; and adipocyte-specific knockout of L...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Xiong, Yan, Page, Jessica C., Narayanan, Naagarajan, Wang, Chao, Jia, Zhihao, Yue, Feng, Shi, Xine, Jin, Wen, Hu, Keping, Deng, Meng, Shi, Riyi, Shan, Tizhong, Yang, Gongshe, Kuang, Shihuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652135/
https://ncbi.nlm.nih.gov/pubmed/29032027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.09.017
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