Llwytho...

Deletion of Lkb1 in adult mice results in body weight reduction and lethality

Liver kinase B1 (Lkb1) plays crucial roles in development, metabolism and survival. As constitutive knockout of Lkb1 in mice leads to embryonic lethality, whether Lkb1 is required for the growth and survival of adult mice is unclear. Here we address this question using a tamoxifen-inducible Lkb1 kno...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Shan, Tizhong, Xiong, Yan, Kuang, Shihuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099919/
https://ncbi.nlm.nih.gov/pubmed/27824128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36561
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