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Characterization of a New Allelic Variant of Triosephosphate Isomerase from the LNCaP Human Prostate Cancer Cell Line: Enzyme Inhibition and Spectroscopic Studies

BACKGROUND: The glycolytic pathway plays an important role in tumor cells. Triosephosphate isomerase (TIM) catalyzes the reversible isomerization of D-glyceraldehyde-3-phosphate (GAP) to dihydroxyacetone phosphate (DHAP) in the glycolysis. Proteomics of a human prostate adenocarcinoma cell line reve...

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Publicado en:Curr Enzym Inhib
Autores principales: Guzmán-Luna, Valeria, Olvera-Rodríguez, Leticia, Bustamante-Villalobos, Peniel, Saab-Rincón, Gloria
Formato: Artigo
Lenguaje:Inglês
Publicado: Bentham Science Publishers 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652080/
https://ncbi.nlm.nih.gov/pubmed/29123462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573408012666160906110330
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