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Adjuvanting an inactivated influenza vaccine with conjugated R848 improves the level of antibody present at 6 months in a nonhuman primate neonate model

Generation of a potent antibody response that can be sustained over time is highly challenging in young infants. Our previous studies using a nursery-reared nonhuman primate model identified R848 conjugated to inactivated influenza virus as a highly immunogenic vaccine for neonates. Here we determin...

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Publicat a:Vaccine
Autors principals: Holbrook, Beth C., D’Agostino, Ralph B., Aycock, S. Tyler, Jorgensen, Matthew J., Hadimani, Mallinath B., King, S. Bruce, Alexander-Miller, Martha A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652071/
https://ncbi.nlm.nih.gov/pubmed/28967521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.09.054
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