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Beyond Ketamine: New Approaches to the Development of Safer Antidepressants

BACKGROUND: Ketamine has been reported to exert rapid and sustained antidepressant effects in patients with depression, including patients with treatment-resistant depression. However, ketamine has several drawbacks such as psychotomimetic/dissociative symptoms, abuse potential and neurotoxicity, al...

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Bibliographic Details
Published in:Curr Neuropharmacol
Main Author: Chaki, Shigeyuki
Format: Artigo
Language:Inglês
Published: Bentham Science Publishers 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652016/
https://ncbi.nlm.nih.gov/pubmed/28228087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X15666170221101054
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