Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration

Muscular dystrophies are severe disorders due to mutations in structural genes, and are characterized by skeletal muscle wasting, compromised patient mobility, and respiratory functions. Although previous works suggested enhancing regeneration and muscle mass as therapeutic strategies, these led to...

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Vydáno v:Nat Commun
Hlavní autoři: Rossi, Giuliana, Bonfanti, Chiara, Antonini, Stefania, Bastoni, Mattia, Monteverde, Stefania, Innocenzi, Anna, Saclier, Marielle, Taglietti, Valentina, Messina, Graziella
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651883/
https://ncbi.nlm.nih.gov/pubmed/29057908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01098-y
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