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Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation
Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we report the mechanism of myosin X (encoded by Myo10)-induced multi-cycle filopodia extension. We found that actin, Arp2/3, vinculin and integrin-β first accumulated at the cell’s leading edge. Myosin...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651867/ https://ncbi.nlm.nih.gov/pubmed/29057977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06147-6 |
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