Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

Obesity is closely associated with increased adipose tissue macrophages (ATMs), which contribute to systemic insulin resistance and altered lipid metabolism by creating a pro-inflammatory environment. Very low-density lipoprotein receptor (VLDLR) is involved in lipoprotein uptake and storage. Howeve...

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Vydáno v:Nat Commun
Hlavní autoři: Shin, Kyung Cheul, Hwang, Injae, Choe, Sung Sik, Park, Jeu, Ji, Yul, Kim, Jong In, Lee, Gha Young, Choi, Sung Hee, Ching, Jianhong, Kovalik, Jean-Paul, Kim, Jae Bum
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651811/
https://ncbi.nlm.nih.gov/pubmed/29057873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01232-w
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