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Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation

Extracellular vesicles (EVs) are small vesicles released by cells to aid cell–cell communication and tissue homeostasis. Human islet amyloid polypeptide (IAPP) is the major component of amyloid deposits found in pancreatic islets of patients with type 2 diabetes (T2D). IAPP is secreted in conjunctio...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ribeiro, Diana, Horvath, Istvan, Heath, Nikki, Hicks, Ryan, Forslöw, Anna, Wittung-Stafshede, Pernilla
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651775/
https://ncbi.nlm.nih.gov/pubmed/28973954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711389114
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