Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

Mycobacterium tuberculosis is a major human pathogen that is able to survive inside host cells and resist immune clearance. Most particularly, it inhibits several arms of the innate immune response, including phagosome maturation or cytokine production. To better understand the molecular mechanisms...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Blanc, Landry, Gilleron, Martine, Prandi, Jacques, Song, Ok-ryul, Jang, Mi-Seon, Gicquel, Brigitte, Drocourt, Daniel, Neyrolles, Olivier, Brodin, Priscille, Tiraby, Gérard, Vercellone, Alain, Nigou, Jérôme
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651758/
https://ncbi.nlm.nih.gov/pubmed/28973928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707840114
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