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Pretransplant 4β‐hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation
AIMS: The CYP3A metric 4β‐hydroxycholesterol (4βOHC) has been shown to correlate with tacrolimus steady‐state apparent oral clearance (CL/F). Recently, pretransplant 4βOHC was shown not to predict tacrolimus CL/F after transplantation in a cohort of renal recipients (n = 79). The goal of the current...
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| Publicado en: | Br J Clin Pharmacol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651327/ https://ncbi.nlm.nih.gov/pubmed/28603840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13343 |
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