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Modulation of Drug Choice by Extended Drug Access and Withdrawal in Rhesus Monkeys: Implications for Negative Reinforcement as a Driver of Addiction and Target for Medications Development

Chronic drug exposure is hypothesized to recruit negative reinforcement processes that increase the magnitude and alter the mechanisms of drug reinforcement. Candidate substrates of negative reinforcement include increased signaling via stress-related neurotransmitters such as corticotropin releasin...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Negus, S. Stevens, Banks, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651207/
https://ncbi.nlm.nih.gov/pubmed/28442370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2017.04.006
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