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Modulation of Drug Choice by Extended Drug Access and Withdrawal in Rhesus Monkeys: Implications for Negative Reinforcement as a Driver of Addiction and Target for Medications Development

Chronic drug exposure is hypothesized to recruit negative reinforcement processes that increase the magnitude and alter the mechanisms of drug reinforcement. Candidate substrates of negative reinforcement include increased signaling via stress-related neurotransmitters such as corticotropin releasin...

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Publicado en:Pharmacol Biochem Behav
Autores principales: Negus, S. Stevens, Banks, Matthew L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651207/
https://ncbi.nlm.nih.gov/pubmed/28442370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2017.04.006
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