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Predicting electrophoretic mobility of tryptic peptides for high-throughput CZE-MS analysis

A multi-parametric sequence-specific model for predicting peptide electrophoretic mobility has been developed using large-scale bottom-up proteomic CE-MS data (5% acetic acid as background electrolyte). Peptide charge (Z) and size (molecular weight, M) are the two major factors determining electroph...

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發表在:Anal Chem
Main Authors: Krokhin, Oleg V., Anderson, Geoff, Spicer, Vic, Sun, Liangliang, Dovichi, Norman J.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651133/
https://ncbi.nlm.nih.gov/pubmed/28208305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b04544
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