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Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma

Resistance to targeted therapy is an ongoing problem for the successful treatment of Stage IV metastatic melanoma. For many patients, the use of targeted therapies, such as BRAF kinase inhibitors, were initially promising yet resistance inevitably occurred. Even after combining BRAF kinase inhibitor...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Keller, Hilary R., Zhang, Xin, Li, Li, Schaider, Helmut, Wells, James W.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650456/
https://ncbi.nlm.nih.gov/pubmed/29088901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18523
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