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Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma

Resistance to targeted therapy is an ongoing problem for the successful treatment of Stage IV metastatic melanoma. For many patients, the use of targeted therapies, such as BRAF kinase inhibitors, were initially promising yet resistance inevitably occurred. Even after combining BRAF kinase inhibitor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Keller, Hilary R., Zhang, Xin, Li, Li, Schaider, Helmut, Wells, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650456/
https://ncbi.nlm.nih.gov/pubmed/29088901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18523
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