Nicotine suppresses apoptosis by regulating α7nAChR/Prx1 axis in oral precancerous lesions

Nicotine, a tumor promoter in tobacco, can increase Peroxiredoxin (Prx1) and nicotinic acetylcholine receptors (nAChRs) in oral squamous cell carcinoma (OSCC). In the present study, we investigate the effects of nicotine in oral precancerous lesions focusing on apoptosis and nAChR/Prx1 signaling. We...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Wang, Chunxiao, Niu, Wenwen, Chen, Hui, Shi, Ni, He, Dian, Zhang, Min, Ge, Lihua, Tian, Zhenchuan, Qi, Moci, Chen, Tong, Tang, Xiaofei
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650400/
https://ncbi.nlm.nih.gov/pubmed/29088845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20506
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