Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion

BACKGROUND: Vascular cognitive impairment (VCI) is a spectrum of cognitive impairment caused by various chronic diseases including aging, hypertension, and diabetes mellitus. Oxidative and inflammatory reactions induced by chronic cerebral hypoperfusion (CHP) are believed to cause VCI. Melatonin is...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Tsai, Tzu-Hsien, Lin, Cheng-Jei, Chua, Sarah, Chung, Sheng-Ying, Yang, Cheng-Hsu, Tong, Meng-Shen, Hang, Chi-Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650343/
https://ncbi.nlm.nih.gov/pubmed/29088788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20382
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