Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion

BACKGROUND: Vascular cognitive impairment (VCI) is a spectrum of cognitive impairment caused by various chronic diseases including aging, hypertension, and diabetes mellitus. Oxidative and inflammatory reactions induced by chronic cerebral hypoperfusion (CHP) are believed to cause VCI. Melatonin is...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tsai, Tzu-Hsien, Lin, Cheng-Jei, Chua, Sarah, Chung, Sheng-Ying, Yang, Cheng-Hsu, Tong, Meng-Shen, Hang, Chi-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650343/
https://ncbi.nlm.nih.gov/pubmed/29088788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20382
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