Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion

BACKGROUND: Vascular cognitive impairment (VCI) is a spectrum of cognitive impairment caused by various chronic diseases including aging, hypertension, and diabetes mellitus. Oxidative and inflammatory reactions induced by chronic cerebral hypoperfusion (CHP) are believed to cause VCI. Melatonin is...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Tsai, Tzu-Hsien, Lin, Cheng-Jei, Chua, Sarah, Chung, Sheng-Ying, Yang, Cheng-Hsu, Tong, Meng-Shen, Hang, Chi-Ling
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650343/
https://ncbi.nlm.nih.gov/pubmed/29088788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20382
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