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Histopathological features of endometrial carcinomas associated with POLE mutations: implications for decisions about adjuvant therapy

AIMS: To characterize the histomorphological features of endometrial carcinomas (ECs) harbouring polymerase ε (POLE) mutations. METHODS AND RESULTS: Forty-three ECs with POLE mutations were compared with a cohort of 202 ECs. Most POLE-mutated ECs were endometrioid [34/43 (79%]; the remaining tumours...

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Dettagli Bibliografici
Pubblicato in:Histopathology
Autori principali: Bakhsh, Salwa, Kinloch, Mary, Hoang, Lien N, Soslow, Robert, Köbel, Martin, Lee, Cheng-Han, McAlpine, Jessica N, McConechy, Melissa K, Gilks, C Blake
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650229/
https://ncbi.nlm.nih.gov/pubmed/26416160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.12878
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