(1)H-MRS metabolites and rate of β-amyloid accumulation on serial PET in clinically normal adults

OBJECTIVE: To assess whether noninvasive proton magnetic resonance spectroscopy ((1)H-MRS) tissue metabolite measurements at baseline can predict an increase in the rate of β-amyloid (Aβ) accumulation on serial PET in clinically normal (CN) older adults. METHODS: Consecutive participants aged 60 yea...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Nedelska, Zuzana, Przybelski, Scott A., Lesnick, Timothy G., Schwarz, Christopher G., Lowe, Val J., Machulda, Mary M., Kremers, Walter K., Mielke, Michelle M., Roberts, Rosebud O., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Jack, Clifford R., Kantarci, Kejal
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649764/
https://ncbi.nlm.nih.gov/pubmed/28842444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004421
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